tristanfaure.com /projects / pfee-lymphoma
Lymphoma MVP (PFEE × HCL)
Treatment-response prediction from histopathology slides — Hospices Civils de Lyon
2026 · IN PROGRESS
Stack
Python · PyTorch · I-JEPA · Foundation Models · Explainability · pytest
Key figures
- Partner
- HCL hospital network
- Extractors
- 4 benchmarked (incl. I-JEPA)
- Tests
- 36 — TDD
- Goal
- Co-authored paper
End-of-studies research project with the Hospices Civils de Lyon: predicting Hodgkin lymphoma treatment response from digitized histopathology slides.
Benchmarks four feature-extraction strategies on tissue patches: an ImageNet ResNet, a pathology foundation model, a from-scratch autoencoder, and I-JEPA — evaluated through linear probes with patient-level aggregation.
Explainability first: attribution maps trace every prediction back to the tissue regions that drove it — a hard requirement for clinical partners.
Built under clinical data-governance constraints (anonymization, auditability); 36 automated tests, TDD workflow. Code is private — no clinical data ever leaves the hospital pipeline.
Links
- Source is private — access on request, via the contact details.
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